The fact I can no longer shoot people in the new Hitman. It's to the point where I just no longer feel like playing it at all. Which sucks, I really like this game and we still have another mission to go.
Hope this gets fixed soon, or ever.
Edit: god damnit, I can't even watch footage either, just started watching a video in the bug report thread and that didn't work out. Now I'm really depressed.