He is already damaged, because of his upbringing.
Regardless, he still was able to develop some emphaty after escaping the asylum:
-simply taking care of things (gardening/animals)
-finding a friend in father Vittorio, who claimed he can see the good in 47
-Diana a friend(?), a colleague, definitely a trustworthy ally (who could pulled such stunts as poisoning 47, or bringing ICA down; yet could count on 47 no matter what)
Before the last game he saw himself as an object. Probably he questioned some of his feelings, but since he was taught to be cold, he pushed those questions out of his mind.
Now the real question is, what is his mental state after the injection of the magic juice.
He claims, that his memories are coming back, but feels like it happened to someone else.