I’ve been having issues recently with HITMAN 2 crashing to desktop at seemingly random times. No specific time or map or anything, however, it might have to do with something in regards to interactions (an NPC or a player opening a door or equipping something with middle mouse click).
Unfortunately there has been no concise reproduction of said crashing, but I will try to post something more concrete. As for my specs:
RTX 2060 (Drivers Updated)
AMD Ryzen 7 2700