The biggest, major changes seem to be…
Coin fetch doesn’t work… But you can just as easily drop and quick grab and lead the target along (if there’s nobody else nearby to also get distracted by it).
FEs only knock out when they explode.
‘The Big One’ no longer electrocutes in puddles.
Hand-guns seem to be harder to use to hit far away targets. Like shooting the virus from the ledge on the other side of the cave, or making objects explode (lawn mowers)…
And if you want to include the tweaked or bugged(?) trespassing system where you can still get SA if spotted trespassing, there’s that too.
I’ve already uninstalled it. The way I see it, every old mission, or what one would classify as the H 2016 game, essentially got an update, and there’s no looking back for me (personally).