I would think no, well at least not as a main entry into the series. As a spin off series following maybe another ICA agent, like Soders. The problem with the 70s and 80s is that 47 wasn’t really active in this period per say. He first joins the ICA in 1999. Before that he was doing jobs with Lucas Grey for Ort-Meyer/Providence.
But from a gameplay perspective no, Assassin’s Creed is a Action Adventure game with stealth elements, often a very simplified approach to stealth. I think a spin off series with other ICA agents would be a better fit here.